Active and Passive smoking with the risk of@breast cancer among women
Objective: To examine the association between smoking and risk of invasive breast
cancer using quantitative
measures of lifetime passive and active smoking exposure among postmenopausal
women. Design Prospective
cohort study. Setting: 40 clinical centres in the United States. Participants: 79990 women aged 50 to
79 enrolled in the Women's Health Initiative Observational Study during
1993 and 1998.
Main outcome measures: Self reported active and passive smoking, pathologically confirmed invasive
Results: In total, 3520 incident cases of invasive breast cancer were identified
during an average of 10.3 years
of follow-up. Compared with women who had never smoked, breast cancer risk
was elevated by 9% among
former smokers and by 16% among current smokers. Significantly higher breast
cancer risk was observed
in active smokers with high intensity and duration of smoking, as well
as with initiation of smoking in the
teenage years. The highest breast cancer risk was found among women who
had smoked for 50 years or
more, compared with all lifetime non-smokers, hazard ratio 1.45, compared
with lifetime non-smokers with
no exposure to passive smoking. An increased risk of breast cancer persisted
for up to 20 years after
Among women who had never smoked, after adjustment for potential confounders,
those with the most
extensive exposure to passive smoking had a 32% excess risk of breast cancer,
compared with those who
had never been exposed to passive smoking. However, there was no significant
association in the other
groups with lower exposure and no clear dose response to cumulative passive
Conclusions: Active smoking was associated with an increase in breast cancer risk
women. There was also a suggestion of an association between passive smoking
and increased risk of
Source: British Medical Journal, March 2011
Look younger for long, quit smoking.
Smoking During Pregnancy
If your health isn't enough to make you quit smoking, then the health of
your baby should be. Smoking
during pregnancy affects you and your baby's health before, during, and
after your baby is born.
The nicotine (the addictive substance in cigarettes), carbon monoxide,
and numerous other poisons
you inhale from a cigarette are carried through your bloodstream and go
directly to your baby.
Smoking while pregnant will:
- Lower the amount of oxygen available to you and your growing baby.
- Increase your baby's heart rate.
- Increase the chances of a spontaneous abortion and stillbirth.
- Increase the risk that your baby is born prematurely and/or born with low
- Increase your baby's risk of developing respiratory problems.
The more cigarettes you smoke per day, the greater your baby's chances
of developing these and
other health problems. There is no "safe" level of smoking while
How Does Secondhand Smoke Affect Pregnancy?
Secondhand smoke (also called passive smoke or environmental tobacco smoke)
is the combination of
smoke from a burning cigarette and smoke exhaled by a smoker. The smoke
that burns off the end of
a cigarette or cigar actually contains more harmful substances. These are
tar, carbon monoxide, nicotine, and
others. If you are regularly exposed to cigarette smoke, you increase your
and your baby's risk of
developing lung cancer, heart disease, emphysema, allergies, asthma, and
other health problems. Babies
exposed to secondhand smoke may also develop reduced lung capacity and
are at higher risk for sudden
infant death syndrome (SIDS).
Cervical cancer risk roughly doubled with passive smoking.
Researchers have found that passive smoking can increase the risk of cervical
cancer by nearly the same
amount as active smoking and roughly double that of no smoke exposure.
Two studies revealed varied results,
and researchers believe that the true figure is somewhere in the middle.
They want more research done to
more accurately ascertain the risks of cervical cancer associated to passive
smoking. In 1963, the cervical
cancer risk increased by 2.1 times in passive smokers, 2.6 times in active
smokers, as compared to those
with no smoke exposure. In 1975, the cervical cancer risk increased by
1.4 times in passive smokers,
1.7 times in active smokers, respectively, as compared to those with no
smoke exposure. The combined
effects of exposure to active and passive smoking suggest its potential
adverse role in cervical carcinogenesis.
Source: summary of medical news story as reported by Cancer Page - Reuters
Health 23 Aug 2011
Smoking and smoking cessation in relation to mortality in women
Most of the excess risk of vascular mortality due to smoking in women may
be eliminated rapidly upon
cessation and within 20 years for lung diseases. Postponing the age of
smoking initiation reduces the risk
of respiratory disease, lung cancer, and other smoking-related cancer deaths
but has a little effect on
the other cause-specific mortality. These data suggest that smoking is
associated with an increased risk
of colorectal cancer mortality but not ovarian cancer mortality.
Cigarette Smoking Increase Cervical Cancer Risk in Women Infected with
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The article was revised in December 2011, by Junhaku Miyamoto, M.D., PhD.
COPYRIGHT(C) 2006-2014. JUNHAKU MIYAMOTO,M.D. ALL RIGHTS RESERVED.